The Necessity to Change

a synchronic and diachronic approach to the change route of address terms in the two recent centuries of persian language

terms of address as an important linguistics items provide valuable information about the interlocutors, their relationship and their circumstances. this study was done to investigate the change route of persian address terms in the two recent centuries including three historical periods of qajar, pahlavi and after the islamic revolution. data were extracted from a corpus consisting 24 novels w...

The existential necessity of midlife change.

As life expectancy in the West increases and companies can no longer promise lifelong security, many businesspeople will need to make major changes during middle age, embarking on a second life and a second career. They must start by getting beyond two pervasive and opposing myths. The first is that midlife marks the onset of decline. Problems do arise during middle age--concerns about health a...

Unproven therapies in clinical research and practice: the necessity to change the regulatory paradigm.

In this article, we challenge 2 fundamental assumptions underlying the current regulation of research for unproven therapies: (1) current regulatory practices serve the best interests of patients and (2) standard definitions allow clear demarcation and rational regulation of such therapies in clinical practice, research, and quality improvement (QI) activities. Our goal is to prompt serious con...

Mammals, Florence and Chemistry: Chance and Necessity in Organizational Change

The Necessity to Use of the National Hemoglobinopathy Registry system for Providing Healthcare Services to Patients

The article is a letter to the editor, so it has no abstract.